Like Protopic, these products are all immunomodulators that affect immune response. Elidel is a product called Pimecrolimus, that is similar to Protopic, but comes in a cream form. The risks and side effects of Elidel, Aldara and Imiquimod are not entirely known, and should be discussed with your doctor. A black box warning was added to Elidel in early 2005, warning that there had been several reported cases of lymphoma or skin cancer following its use. Some doctors dispute these findings, suggesting the numbers of cancer and lymphoma cases reported are no higher than would be seen in the general population.